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South Carolina's
November 2, 2010 General Election
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| U.S. Senate | Incumbent Jim DeMint (R) - SAOVA ENDORSED | ||
| 1st District - OPEN SEAT | State Rep. Tim Scott (R) – Reviewed questionnaire and declined to answer | ||
| 2nd District | Incumbent A.G. "Joe" Wilson (R) - SAOVA ENDORSED | ||
| 3rd District - OPEN SEAT | Jane B. Dyer (D) v state Rep Jeff Duncan (R) NONRESPONSIVE TO QUESTIONNAIRE |
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| 4th District - OPEN SEAT | Paul Corden (D) v Trey Gowdy (R) NONRESPONSIVE TO QUESTIONNAIRE |
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| 5th District | Incumbent John Spratt (D) -
Animal Rightist Endorsed v Mick Mulvaney (R) - SAOVA ENDORSED - WON |
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| 6th District | Incumbent James Clyburn (D) - Animal Rightist Endorsed | ||
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Animal Rightist endorsed and/or sponsors of AR supported state legislation
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SAOVA endorsed state legislators
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